Preheat your oven to 350°F (175°C).
Cook the elbow macaroni according to the package instructions, drain, and set aside.
In a large bowl, whisk together the eggs, evaporated milk, whole milk, melted butter, Dijon mustard, garlic powder, onion powder, cayenne pepper, salt, and black pepper.
Stir in the grated cheeses (sharp cheddar and mozzarella) until well combined.
Add the cooked macaroni to the cheese mixture and stir until the pasta is coated evenly.
Pour the mixture into a greased 9x13 baking dish.
Top with breadcrumbs for a crunchy finish.
Bake for 30-40 minutes, or until the top is golden and bubbly.
Allow it to cool slightly before serving.