Prepare the stuffing mixture: Sauté the vegetables and aromatics until soft and fragrant. Combine with seafood, breadcrumbs, herbs, butter, and seasonings until the mixture becomes moist and holds together.
Prepare the catfish fillets: Pat the catfish fillets dry and season both sides evenly. Carefully create space for the stuffing without breaking the fillets.
Stuff the catfish fillets: Add the prepared stuffing onto each fillet, making sure not to overfill. Fold or arrange the fillets so the stuffing stays secure during baking.
Bake the stuffed catfish: Place the stuffed fillets in a baking dish and bake until the fish becomes flaky, the center is fully cooked, and the edges turn lightly golden brown.
Rest and serve: Allow the stuffed catfish to rest briefly before serving. Garnish with fresh herbs and lemon wedges for extra brightness.