Prepare the Roast: Pat the chuck roast dry with paper towels. Rub the roast with olive oil to help the seasoning stick.
Season the Roast: In a small bowl, combine garlic powder, onion powder, smoked paprika, rosemary, salt, and pepper. Rub the seasoning mixture all over the roast.
Preheat the Air Fryer: Preheat the air fryer to 400°F (200°C) for about 5 minutes.
Cook the Roast: Place the seasoned chuck roast in the air fryer basket. Cook for 25-30 minutes, flipping halfway through the cooking time to ensure even browning. Use a meat thermometer to check the internal temperature (it should reach about 135°F for medium-rare or 145°F for medium).
Rest the Roast: Once done, remove the roast from the air fryer and let it rest for 10 minutes before slicing to allow the juices to redistribute.